FlyBase Allele Report: Dmel\RpL38[NC21]

General Information

Symbol

Dmel\RpL38^NC21

Species

D. melanogaster

Name

FlyBase ID

FBal0150415

Feature type

allele

Associated gene

Dmel\RpL38

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Myster and Peifer, 2003.9.11)

Progenitor genotype

Cytology

Description

Nucleotide substitution: C?T. Point mutation 7 bases upstream of the predicted transcription start site.

(Marygold et al., 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2R)247)

(Coulthard et al., 2010)

lethal (with Df(2R)M41A2)

(Coulthard et al., 2010)

lethal (with RpL38^2b1)

(Marygold et al., 2005)

lethal (with RpL38^2b2)

(Marygold et al., 2005)

lethal (with RpL38^45-72)

(Marygold et al., 2005)

lethal | recessive

(Myster and Peifer, 2003.9.11)

Minute (with RpL38^2b1)

(Marygold et al., 2005)

Minute (with RpL38^2b2)

(Marygold et al., 2005)

Minute (with RpL38^45-72)

(Marygold et al., 2005)

Minute (with RpL38^KPL1)

(Marygold et al., 2005)

Minute (with RpL38^P3)

(Marygold et al., 2005)

Minute | dominant

(Marygold et al., 2005)

partially lethal (with RpL38^KPL1)

(Marygold et al., 2005)

partially lethal (with RpL38^P3)

(Marygold et al., 2005)

visible (with RpL38^2b1)

(Marygold et al., 2005)

visible (with RpL38^2b2)

(Marygold et al., 2005)

visible (with RpL38^45-72)

(Marygold et al., 2005)

Phenotype Manifest In

chaeta

(Marygold et al., 2005)

chaeta (with RpL38^2b1)

(Marygold et al., 2005)

chaeta (with RpL38^2b2)

(Marygold et al., 2005)

chaeta (with RpL38^45-72)

(Marygold et al., 2005)

chaeta (with RpL38^KPL1)

(Marygold et al., 2005)

chaeta (with RpL38^P3)

(Marygold et al., 2005)

wing (with RpL38^2b1)

(Marygold et al., 2005)

wing (with RpL38^2b2)

(Marygold et al., 2005)

wing hair (with RpL38^2b1)

(Marygold et al., 2005)

wing margin (with RpL38^45-72)

(Marygold et al., 2005)

wing vein | ectopic (with RpL38^2b1)

(Marygold et al., 2005)

wing vein | ectopic (with RpL38^2b2)

(Marygold et al., 2005)

Detailed Description

Statement

Reference

Heterozygous adults have a very weak Minute bristle phenotype. Heterozygotes show no delay in eclosion compared to control flies. RpL38^2b1/RpL38^NC21 animals show 2% viability and have a strong Minute small-bristle phenotype. These animals also show extra venation on the wing and wing hair polarity is often disorganised. RpL38^45-72/RpL38^NC21 animals show 5% viability. These animals also show notches on the wing margin. RpL38^2b2/RpL38^NC21 animals show 6% viability and have a strong Minute small-bristle phenotype. These animals also show extra venation on the wing. RpL38^P3/RpL38^NC21 animals show 17% viability and have a strong Minute small-bristle phenotype. RpL38^KPL1/RpL38^NC21 animals show 31% viability and have a weak Minute small-bristle phenotype.

(Marygold et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Induced on: cn¹ bw¹.

(Myster and Peifer, 2003.9.11)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

NC21

(Coulthard et al., 2010)

RpL38^NC21

(Coulthard et al., 2010)

l(2)41Af^NC21

(Myster and Peifer, 2003.9.11)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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