FB2026_02 , released June 18, 2026
Allele: Dmel\achiZ3922
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General Information
Symbol
Dmel\achiZ3922
Species
D. melanogaster
Name
FlyBase ID
FBal0150562
Feature type
allele
Associated gene
Dmel\achi
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ayyar et al., 2003)
Progenitor genotype
Cytology
Description

Premature stop codon in exon 5.

(Ayyar et al., 2003)

Amino acid replacement: ??term.

(Ayyar et al., 2003)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:12,513,430..12,513,430 [-]
Nucleotide change:

C12513430T

Amino acid change:

Q230term | achi-PA; Q230term | achi-PC; Q230term | achi-PD

Reported amino acid change:

Q230term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. The line is found to be a combination of two alleles, achiZ3922 and visZ3922.

(Ayyar et al., 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      visZ3922, achiZ3922 animals are viable. Their males are completely sterile and females crossed to wild-type males exhibit a delay in egg laying. testes from homozygous males have a complete absence of mature sperm. Stages up to late spermatocyte are present but no meiotic stages can be seen.

      (Ayyar et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Induced with: visZ3922 The zaa line is found to be a combination of two alleles, achiZ3922 and visZ3922.

      (Ayyar et al., 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Z3922
      (Ayyar et al., 2003)
      achiZ3922
      (Doggett et al., 2011, Jiang et al., 2007)
      zaa
      Name Synonyms
      Secondary FlyBase IDs
        References (4)