Somatic clones of Moe^X5 homozygous cells induced in 2nd or third instar rarely survive in the adult eye, but ommatidia containing reduced numbers of photoreceptors are common.

Moe^X5 germ-line clone oocytes have normal microtubule polarity, but the organization of the actin cytoskeleton is disrupted: microfilaments are more loosely bound to the posterior and lateral cortex of the oocyte than in wild-type. In Moe^X5 germline clone nurse cells, the regular arrangement of the cortical actin network is lost. Instead, microfilaments are localized in a few aggregates that radiate from the cell surface, forming abnormal structures that resemble flowers. However, the actin cables that maintain nurse cell nuclei and the actin-rich ring canals appear normal.