FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SPRNAi.UAS
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General Information
Symbol
Dmel\SPRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0150993
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-SP-IR
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of two copies of a 305bp of SP arranged in an inverted repeat orientation.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Females previously mated to males expressing Acp70AdsRNA.Scer\UAS under the control of Scer\GAL4Acp26Aa.PC remate more frequently and sooner than do females mated to control males.

Females mated to males expressing Acp70AdsRNA.Scer\UAS under the control of Scer\GAL4Acp26Aa.PC lay significantly fewer eggs in the period between their first and second matings than females mated to control males.

Control males have a significantly higher per-mating reproductive success in a lifetime assay than males expressing Acp70AdsRNA.Scer\UAS under the control of Scer\GAL4Acp26Aa.PC.

Females mated to males expressing Acp70AdsRNA.Scer\UAS under the control of Scer\GAL4Acp26Aa.PC ("SP knock-down" males) have significantly higher fitness and higher lifetime reproductive success than controls.

Females mated to males expressing Acp70AdsRNA.Scer\UAS under the control of Scer\GAL4Acp26Aa.PC ("SP knock-down" males) are significantly more receptive than females mated to control males. At 24 hours after mating, the receptivity of females mated to SP knock-down males is intermediate between that of females mated to control males and that of virgin females. By 48 hours after mating the receptivity of females mated to SP knock-down males is similar to that of virgin females. Females mated to SP knock-down males lay significantly fewer eggs than females mated to control males. On days 1-2 after mating, females mated to SP knock-down males lay eggs at a level intermediate between that of females mated to control males and that of virgin females. Thereafter, the n umber of eggs deposited by females mated to SP knock-down males is similar to that of virgin females. At 6, 24 and 48 hours after mating, females mated to SP knock-down males show lower ovulation than females mated to control males and significantly higher ovulation than virgin females. There is no significant difference in egg fertility between females mated to SP knock-down males and females mated to control males on days 1 and 3 after mating. On day 5 after mating the egg fertility of females mated to control males is significantly lower than that of females mated to SP knock-down males.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Acp70AdsRNA.Scer\UAS
SPRNAi.UAS
SPdsRNA.Scer\UAS
SPdsRNA.UAS
Name Synonyms
Secondary FlyBase IDs
    References (5)