FlyBase Allele Report: Dmel\toe[UAS.cAa]

General Information

Symbol

Dmel\toe^UAS.cAa

Species

D. melanogaster

Name

FlyBase ID

FBal0151378

Feature type

allele

Associated gene

Dmel\toe

Associated Insertion(s)

Carried in Construct

P{UAS-toe.A}

Also Known As

UAS-toe

Key Links

Transgenic product class

wild_type

(Aldaz et al., 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Aldaz et al., 2003)

Mutagen

in vitro construct

(Aldaz et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-toe.A}

Cytology

Description

Expression of the toe ORF is under the control of UASt sequences.

(Aldaz et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

toe

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

abnormal planar polarity, with Scer\GAL4^MS248

(Aldaz et al., 2003)

Phenotype Manifest In

macrochaeta & scutum, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

macrochaeta & scutum, with Scer\GAL4^MS248

(Aldaz et al., 2003)

microchaeta | ectopic, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

microchaeta | ectopic, with Scer\GAL4^MS248

(Aldaz et al., 2003)

scutellum, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

scutellum, with Scer\GAL4^MS248

(Aldaz et al., 2003)

scutum, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

Detailed Description

Statement

Reference

In the scutellum of toe^Scer\UAS.cAa flies with Scer\GAL4^MS248 or Scer\GAL4^MD-638, the presence of ectopic microchaetes and the changes in morphology suggest a transformation into scutum. In addition there is an abrupt change in polarity of the microchaetes and macrochaetes close to the border of the transformation.

(Aldaz et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

toe^UAS.cAa/Scer\GAL4^ey.PH is a suppressor | partially of eye phenotype of Scer\GAL4^ey.PH, fng^UAS.cKa

(Dominguez et al., 2004)

toe^UAS.cAa, Scer\GAL4^ey.PH is a suppressor | partially of eye phenotype of N^ECN.UAS, Scer\GAL4^ey.PH

(Dominguez et al., 2004)

Scer\GAL4^eyg-gv5/toe^UAS.cAa is a suppressor | partially of dorsocentral bristle phenotype of eyg^gv5/Df(3L)iro-2

(Aldaz et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Scer\GAL4^ey.PH-mediated expression of toe^Scer\UAS.cAa partially rescues the small eye phenotype seen in flies where fng^Scer\UAS.cKa or N^ECN.Scer\UAS is expressed under the control of Scer\GAL4^ey.PH.

(Dominguez et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

36538

w^*; P{UAS-toe.A}2/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

toe^Scer\UAS.cAa

toe^UAS.cAa

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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