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General Information
Symbol
Dmel\sl5
Species
D. melanogaster
Name
FlyBase ID
FBal0151487
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

sl5 is a deletion of the sequence TGATAGCCGCACGTC, this results in the deletion of the amino acids LIAAR, aa#1115-1119. The remaining C in the codon for aa#1115 is fused to the remaining AT of codon #1120, thus retaining the His encoded by codon #1120.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The sequence "TGATAGCCGCACGTC" is deleted, resulting in the deletion of amino acids 1115-1119 (LIAAR) from the expressed product. The remaining C amino acid residue from before the deleted sequence is fused to the AT of codon 1120, meaning that the mutated protein retains the His encoded by codon 1120.

In-fame deletion of 15bp that removes 5 amino acids from the C2 domain.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Approximately 30-50% of ommatidia have extra R7 cells in homozygous females. The length of the wing is approximately 80% normal length in homozygous females, and ectopic wing veins are seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
sl5
Name Synonyms
Secondary FlyBase IDs
    References (2)