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General Information
Symbol
Dmel\lolaORE119
Species
D. melanogaster
Name
FlyBase ID
FBal0151748
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C10505302T

Reported nucleotide change:

C37988T

Amino acid change:

P712L | lola-PB; P712L | lola-PC

Reported amino acid change:

P712L|lola-PB

Comment:

P712 is replaced by L in the C5-8,V23 isoforms.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: T37988C. Amino acid replacement: P712L.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

No gonad defects are observed in homozygous lolaORE119 mutant embryos.

lolaORE119 MARCM clones show normal antero-dorsal projection neuron (PN) targeting, but lateral and ventral PNs show a loss of targeting.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

lola[+]/lolaORE119 is an enhancer of wing margin phenotype of ct53d

Additional Comments
Genetic Interactions
Statement
Reference

The wing nicking phenotype caused by expression of domdsRNA.Sym.Scer\UAS under the control of Scer\GAL4bbg-C96 is enhanced if the flies are also carrying lolaORE119.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)