P712L | lola-PB; P712L | lola-PC
P712 is replaced by L in the C5-8,V23 isoforms.
Nucleotide substitution: T37988C. Amino acid replacement: P712L.
lethal (with Df(2R)BSC595)
lethal (with Df(2R)stan2)
lethal | recessive
neuroanatomy defective | somatic clone
partially lethal (with lolac46)
viable (with lolaORC4)
viable (with lolaORE50)
viable (with lolaORE120)
No gonad defects are observed in homozygous lolaORE119 mutant embryos.
lolaORE119 MARCM clones show normal antero-dorsal projection neuron (PN) targeting, but lateral and ventral PNs show a loss of targeting.
lolaORE119 is an enhancer of visible phenotype of Scer\GAL4bbg-C96, domdsRNA.Sym.UAS
lolaORE119 is an enhancer of wing margin phenotype of Scer\GAL4bbg-C96, domdsRNA.Sym.UAS
lola[+]/lolaORE119 is an enhancer of wing margin phenotype of ct53d
The wing nicking phenotype caused by expression of domdsRNA.Sym.Scer\UAS under the control of Scer\GAL4bbg-C96 is enhanced if the flies are also carrying lolaORE119.
lolaORE119 is not rescued by lolaL.UAS/Scer\GAL4unspecified