FlyBase Allele Report: Dmel\eyg[UAS.cAa]

General Information

Symbol

Dmel\eyg^UAS.cAa

Species

D. melanogaster

Name

FlyBase ID

FBal0151937

Feature type

allele

Associated gene

Dmel\eyg

Associated Insertion(s)

Carried in Construct

P{UAS-eyg.A}

Also Known As

UAS-eyg

Key Links

Transgenic product class

wild_type

(Aldaz et al., 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Aldaz et al., 2003)

Mutagen

in vitro construct

(Aldaz et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-eyg.A}

Cytology

Description

Expression of the eyg ORF is under the control of UASt sequences.

(Aldaz et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

eyg

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity, with Scer\GAL4^455.2

(Aldaz et al., 2003)

abnormal planar polarity, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

abnormal planar polarity, with Scer\GAL4^MS248

(Aldaz et al., 2003)

abnormal planar polarity, with Scer\GAL4^pnr-MD237

(Aldaz et al., 2003)

abnormal planar polarity, with Scer\GAL4^ush-MD751

(Aldaz et al., 2003)

visible, with Scer\GAL4^MS248

(Aldaz et al., 2005)

Phenotype Manifest In

macrochaeta & scutum, with Scer\GAL4^455.2

(Aldaz et al., 2003)

macrochaeta & scutum, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

macrochaeta & scutum, with Scer\GAL4^MS248

(Aldaz et al., 2003)

macrochaeta & scutum, with Scer\GAL4^pnr-MD237

(Aldaz et al., 2003)

macrochaeta & scutum, with Scer\GAL4^ush-MD751

(Aldaz et al., 2003)

macrochaeta | ectopic, with Scer\GAL4^MS248

(Aldaz et al., 2005)

microchaeta | ectopic, with Scer\GAL4^455.2

(Aldaz et al., 2003)

microchaeta | ectopic, with Scer\GAL4^ap-md544

(Aldaz et al., 2003)

microchaeta | ectopic, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

microchaeta | ectopic, with Scer\GAL4^MS248

(Aldaz et al., 2003)

microchaeta | ectopic, with Scer\GAL4^pnr-MD237

(Aldaz et al., 2003)

microchaeta | ectopic, with Scer\GAL4^ush-MD751

(Aldaz et al., 2003)

scutellum, with Scer\GAL4^455.2

(Aldaz et al., 2003)

scutellum, with Scer\GAL4^ap-md544

(Aldaz et al., 2003)

scutellum, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

scutellum, with Scer\GAL4^MS248

(Aldaz et al., 2005, Aldaz et al., 2003)

scutellum, with Scer\GAL4^pnr-MD237

(Aldaz et al., 2003)

scutellum, with Scer\GAL4^ush-MD751

(Aldaz et al., 2003)

scutum, with Scer\GAL4^455.2

(Aldaz et al., 2003)

scutum, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

scutum, with Scer\GAL4^MS248

(Aldaz et al., 2003)

scutum, with Scer\GAL4^pnr-MD237

(Aldaz et al., 2003)

scutum, with Scer\GAL4^ush-MD751

(Aldaz et al., 2003)

scutum | ectopic, with Scer\GAL4^MS248

(Aldaz et al., 2005)

wing, with Scer\GAL4^MD-638

(Aldaz et al., 2003)

Detailed Description

Statement

Reference

Expression of eyg^Scer\UAS.cAa under the control of Scer\GAL4^MS248 results in the scutellum being replaced by a scutum-like pattern in mirror-image orientation. Macrochaetae are present in the duplicated structure.

(Aldaz et al., 2005)

In the scutellum of eyg^Scer\UAS.cAa flies with Scer\GAL4^455.2, Scer\GAL4^MS248, Scer\GAL4^ush-MD751, Scer\GAL4^pnr-MD237, or Scer\GAL4^MD-638, the presence of ectopic microchaetes and the changes in morphology observed suggest a transformation into scutum. In addition there is an abrupt change in polarity of the microchaetes and macrochaetes close to the border of the transformation. The wings of eyg^Scer\UAS.cAa; Scer\GAL4^MD-638 flies are badly deformed, and exhbit a patch of sclerotised tissue at their center, suggesting partial transformation towards a notum fate. eyg^Scer\UAS.cAa ; Scer\GAL4^ap-md544 the scutellum is absent but there is no indication of scutellum to scutum transformation.

(Aldaz et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Flies expressing both hth^Scer\UAS.cPa and eyg^Scer\UAS.cAa under the control of Scer\GAL4^MS248 have duplicated notum structures, but the duplicated structures do not contain macrochaetae.

(Aldaz et al., 2005)

In eyg^Scer\UAS.cAa; Scer\GAL4^MD-638; ara^Scer\UAS.cGa flies, the wing is replaced by a notum duplication, and the scutellar regions of the normal and the duplicated notum are transformed towards scutum. i.e.- the phenotypes due to eyg and ara overexpression with this driver appear to be additive.

(Aldaz et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

eyg^Scer\UAS.cAa

eyg^UAS.cAa

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close