FB2026_02 , released June 18, 2026
Allele: Dmel\eyaD493N.S670A.UAS
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General Information
Symbol
Dmel\eyaD493N.S670A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0151946
Feature type
allele
Associated gene
Dmel\eya
Associated Insertion(s)
Carried in Construct
P{UAS-eya.D493N.S670A}
Key Links
Transgenic product class
missense_variant
(Tootle et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Tootle et al., 2003)
Mutagen
in vitro construct
(Tootle et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-eya.D493N.S670A}
Cytology
Description

Expression of mutated eya is under the control of UAS sequences (carries the amino acid replacements D493N and S670A).

(Tootle et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
eya
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      eyaD493N.S670A.UAS/Scer\GAL4dpp.blk1 partially rescues eya2

      (Tootle et al., 2003)
      Comments

      Eye formation in eya2 flies is rescued by eyaD493N.S670A.Scer\UAS; Scer\GAL4dpp.blk1 with a penetrance of under 5% percent (compared to 100% penetrance due to rescue by eyaScer\UAS.cHa). The resulting eyes are under 5% wild-type size (compared with around 50-80% due to rescue by eyaScer\UAS.cHa).

      (Tootle et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      eyaD493N.S670A.Scer\UAS
      eyaD493N.S670A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)