FB2026_02 , released June 18, 2026
Allele: Dmel\GatA50
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General Information
Symbol
Dmel\GatA50
Species
D. melanogaster
Name
FlyBase ID
FBal0152100
Feature type
allele
Associated gene
Dmel\GatA
Associated Insertion(s)
Carried in Construct
Also Known As
50-40
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Nucleotide substitution: T?A.

    (Morris et al., 2008)

    T to A substitution in intron 3 donor sequence, predicted to disrupt splicing between 174Y and 175A.

    (Morris et al., 2008)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:19,028,113..19,028,113 [-]
    Nucleotide change:

    T19028113A

    Reported nucleotide change:

    T?A

    Comment:

    T to A substitution in splice donor site.

    (Morris et al., 2008)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygous clones in the eye result in small and misshapen eyes which have various differentiation defects, including cuticle scars and ectopic bristles.

        (Morris et al., 2008)

        Homozygous clones can be recovered in the eye. Females containing homozygous germ-line clones show defects in early oogenesis. The mutant egg chambers contain underreplicated nurse cells whose nuclei retain polytene morphology beyond stage 5. The karyosomes are fragmented or stringy. This allele predominantly affects the karyosome.

        (Morris et al., 2003)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Selected as: a mutation that results in a failure to produce eggs when females carry homozygous germ-line clones.

        (Morris et al., 2003)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (5)
        Reported As
        Symbol Synonym
        50-40
        (Morris et al., 2008, Morris et al., 2003)
        GatA50
        benedict50-40
        gatA50-40
        gatA50
        (Morris et al., 2008)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)