FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\aos5F4
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General Information
Symbol
Dmel\aos5F4
Species
D. melanogaster
Name
FlyBase ID
FBal0152120
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

About 43% of ommatidia in argosΔ7/argos5F4 animals exhibit extra R cells. Of those that ommatidia that remain about 45% exhibit misrotations, about 5% exhibit achirality, and none exhibit the wrong chirality. About 16% of ommatidia in argos5F4/argosrlt animals exhibit extra R cells. Of those that ommatidia that remain about 53% exhibit misrotations, about 2% exhibit achirality, and about 0.3% exhibit the wrong chirality.

In argos5F4/argosΔ7 transheterozygotes 45% of adult ommatidia have extra photoreceptors. Many of the ommatidia with a normal complement of photoreceptor cells have polarity defects up to 59% of ommatidia are misrotated, while only 5% appear achiral and usually less than 1% have the wrong chirality. It appears that a transformation of mystery cells to photoreceptor R3/R4 is the cause of the extra photoreceptor cells. When the eye discs of these mutants are examined about 60% of immature clusters exhibit extra photoreceptor precursor cells. In row 7-8 the number of extra cells decreases to about 25%. In the adult only about 15% of clusters have ectopic R3/R4 cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

aos5F4 is an enhancer of ommatidium phenotype of fz20/fz19

Suppressor of
Statement
Reference

aos5F4 is a suppressor of ommatidium phenotype of Ras64BV14.Act5C

Additional Comments
Genetic Interactions
Statement
Reference

The addition of argos5F4/+ enhances the eye cell polarity phenotype seen in fz19/fz20 animals. Heterozygotes suppress the ommatidial polarity defects seen in Ras64BV14.Act5C.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
aos5F4
argos5F4
Name Synonyms
Secondary FlyBase IDs
    References (2)