FB2026_02 , released June 18, 2026
Allele: Dmel\Or22aUAS.Tag:MYC
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General Information
Symbol
Dmel\Or22aUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0152330
Feature type
allele
Associated gene
Dmel\Or22a
Associated Insertion(s)
Carried in Construct
P{UAS-Or22a.myc}
Key Links
Transgenic product class
wild_type
(Dobritsa et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Dobritsa et al., 2003)
Mutagen
in vitro construct
(Hallem et al., 2004, Dobritsa et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-Or22a.myc}
Cytology
Description

UASt regulatory sequences drive expression of Or22a tagged at the N-terminal end with Tag:MYC.

(Dobritsa et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Or22a
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When Or22aScer\UAS.T:Hsap\MYC is driven by Scer\GAL4Or22a.8197 in Df(2L)dp-79b/Dp(2;2)dppd21 (Δhalo) flies, mutant animals exhibit a strong response to exposure to pentyl acetate, ethyl butyrate or 1-octen-3-ol in the ab3A neuron. A strong response is not seen in response to exposure to ethyl acetate, methyl salicylate, 1-hexanol, E2-hexanal, 2,3-butanedione, 2-heptanone or geranyl acetate.

      (Hallem et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Or22a.8197/Or22aUAS.Tag:MYC rescues Dp(2;2)dppd21/Df(2L)dp-79b

      (Dobritsa et al., 2003)
      Comments

      Or22aScer\UAS.T:Hsap\MYC expressed under the control of Scer\GAL4Or22a.8197 rescues the response of the ab3A neurons in the antenna to odours in Df(2L)dp-79b/Dp(2;2)dppd21 flies.

      (Dobritsa et al., 2003)

      Or22aScer\UAS.T:Hsap\MYC expressed under the control of Scer\GAL4Or22a.8197 rescues the response of the ab3A neurons in the antenna to odours in flies mutant for "Δhalo" (in which Df(2L)dp-79b and Dp(2;2)dppd21 are recombined onto the same chromosome to create a synthetic deficiency).

      (Dobritsa et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Or22aScer\UAS.T:Hsap\MYC
      Or22aUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (4)