FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mkp35J4
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General Information
Symbol
Dmel\Mkp35J4
Species
D. melanogaster
Name
FlyBase ID
FBal0152421
Feature type
allele
Associated gene
Dmel\Mkp3
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Rintelen et al., 2003)
Progenitor genotype
Mkp35
(Rintelen et al., 2003)
Cytology
Description

The P{EP}Mkp311 insertion present on the Mkp35 chromosome has been precisely excised.

(Rintelen et al., 2003)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mkp35J4 embryos exhibit a mild tracheal phenotype; 12% of dorsal branches between metameres 4 to 8 show a delay in reaching the dorsal midline at stage 14-15, compared to a delay in only 0.3% of wild-type dorsal branches.

      (Cela and Llimargas, 2006)

      Analysis of mosaic ommatidia indicates that Mkp3 function is dispensible in any photoreceptor and is also not required in the mystery cell. However, there is a strong autonomous Mkp3 component in the R3 and R4 cells.

      (Rintelen et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Mkp31/Mkp35J4, PTP-ERXE-3022, rl10a has viable phenotype

      (Rintelen et al., 2003)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dmkp35J4
      (Rintelen et al., 2003)
      Mkp35J4
      (Cela and Llimargas, 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)