FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RhoGEF64CUAS.cBa
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General Information
Symbol
Dmel\RhoGEF64CUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Bashaw
FlyBase ID
FBal0152490
Feature type
allele
Associated gene
Dmel\RhoGEF64C
Associated Insertion(s)
Carried in Construct
P{UAS-RhoGEF64C.B}
Key Links
Transgenic product class
wild_type
(Bashaw et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bashaw et al., 2001)
Mutagen
in vitro construct
(Bashaw et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-RhoGEF64C.B}
Cytology
Description

UASt regulatory sequences drive expression of full length RhoGEF64C.

(Bashaw et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
RhoGEF64C
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Gef64CScer\UAS.cBa under the control of Scer\GAL4elav.PLu results in many axons abnormally projecting across the midline. The commissures are thicker than normal and there is a reduction in the longitudinal axon tracts.

      (Bashaw et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Gef64CScer\UAS.cBa rescues the invagination defects seen in the posterior spiracles of embryos expressing Rho1N19.Scer\UAS under the control of Scer\GAL4ems.HRE, resulting in normal spiracular chamber formation in 73.8% of cases.

      (Simões et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Gef64CScer\UAS.cBa
      RhoGEF64CScer\UAS.cBa
      RhoGEF64CUAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Bashaw
      (Bashaw et al., 2001)
      Secondary FlyBase IDs
        References (3)