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General Information
Symbol
Dmel\l(3)mbtGM79
Species
D. melanogaster
Name
FlyBase ID
FBal0155049
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

T27268046A

Amino acid change:

M964K | l(3)mbt-PB

Reported amino acid change:

M964K

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: M964K.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos resulting from l(3)mbtGM79 germ-line clones or laid by l(3)mbtGM79/Df(3R)mbtPE3 mothers have reduced numbers of germ cells compared to wild-type embryos. The synchrony of mitotic divisions is disrupted during cleavage stages in these embryos: There are nuclei in almost all stages of mitosis within a single embryo at a given time point, although there is some evidence of limited local synchrony. Gaps in the density of nuclei can sometimes be seen. Despite these defects, no centrosomal defects are evident and mitotic spindles appear normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
l(3)mbtGM79
Name Synonyms
Secondary FlyBase IDs
    References (1)