No mutation has been detected in the open reading frame.
ed2B8/edm1 embryos show hyperplasia of the central nervous system. edk01102/edm1 animals usually die as pupae, but adult escapers are sometimes produced in low density cultures. These escapers have mild defects in the leg; the legs have the correct number of segments, but the sex combs are malformed in males. They also have a rough eye phenotype. edm1/edts animals shifted to the non-permissive temperature (29oC) for 3 days at the end of larval stage 2 and then shifted back to 18oC can survive to adulthood. These flies have extra macrochaetae, which are generally found next to macrochaetae that are normally present in wild-type flies. The density of microchaetae is also increased and the flies have a rough eye phenotype. edm1/edts flies grown at 25oC have irregular thickenings of wing vein L2.
edm1/edts has wing vein L2 phenotype, enhanceable by Deltavi1/Dl[+]
Deltavi1, edm1/edts has posterior wing cell phenotype
Deltavi1/Dl[+], edm1/edts has posterior wing cell phenotype