Myc²/+ heterozygote adult females are significantly lighter compared to wild-type but eclose earlier under limited nutrition than wild-type controls. They also have smaller wings with fewer and smaller cells compared to wild-type.

dm² germline stem cell (GSC) clones behave similarly to control GSC clones, and have normal division rates - GSC maintenance is not affected.

dm¹/dm² females are small with slender bristles and are sterile. dm² hemizygous eggs hatch at near normal rates, and many mutant larvae are viable for several days following hatching. However, they remain small and only about 20% progress to pupation and none eclose as adult flies. Oogenesis in dm² homozygous germ-line clones arrests early. Egg chambers with in which all the germ-line cells are part of a dm² homozygous clone are abnormally small for their position in the ovariole. Oocyte specification occurs normally in these egg chambers. The recovery of follicles in which all 16 germline cells are homozygous for dm² indicates that at least four cycles of mitotic division occur following induction of a germ-line clone. The decrease in germ-cell size in these germ-line clones is likely due to a decrease in endoreplication as BrDU incorporation is significantly lower in these germ-cells than in wild-type. In egg chambers in which only some of the germ-cells are dm² homozygous, the nuclei of mutant nurse cells mutant are dramatically reduced in size compared with the wild-type nuclei in the same cyst. Chromosomal morphology in these nuclei remains condensed after it has become diffuse in wild-type nuclei in the same cysts. Compared to ovarian follicle cell nuclei in the same late stage cysts, the nuclei of dm²/+ ovarian follicle cells are approximately half normal size and the nuclei of dm² homozygous cells about a 10th normal size. Some reduction in the size of dm² homozygous ovarian follicle cells compared to wild type is seen at stage 5. BrDU incorporation is significantly reduced in post mitotic dm² homozygous ovarian follicle cells compared to wild-type cells in the same cyst, suggesting a decrease in endoreplication. Despite this, chorion gene amplification in stage 11 egg chambers appears occur normally in dm² homozygous clone cells. Egg chambers in which all germline cells are homozygous for dm² remain small and immature: egg chambers that should be between stages 8-10, as judged by their position in the ovariole, instead have the appearance of stage 6-7 egg chambers. The wild-type follicle cells that surrounded the mutant germline also exhibit unusual patterns of gene expression. When a wild-type germline is surrounded by an epithelium in which every follicle cell is dm²/dm², the resulting egg chambers are severely delayed in their growth and maturation, and rarely progress to a stage in which yolk uptake can be detected in the oocyte.