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General Information
Symbol
Dmel\Sdcunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0155817
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhanced by
    Enhancer of
    Statement
    Reference
    NOT Enhancer of
    Statement
    Reference
    Other
    Phenotype Manifest In
    Enhanced by
    Enhancer of
    NOT Enhancer of
    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The number of ventral muscles that cross the midline in lea1 Sdcunspecified double mutant embryos is significantly increased compared to either single mutant. The longitudinal axons collapse along the ventral midline and form a single fascicle. roboQ1-15 Sdcunspecified embryos do not show enhancement of the muscle and central nervous system midline crossing phenotypes seen in roboQ1-15 embryos. sli2 Sdcunspecified double heterozygous embryos have additional longitudinal transverse muscles. The number of Fas2-expressing inner fascicles that cross the midline in the double heterozygotes (3.3%) is increased compared to sli2 single heterozygotes (0.6%). Sdcunspecified homozygous embryos that are also heterozygous for one of roboQ1-15, lea1 or sli2 show an enhanced axonal guidance defect with multiple midline crossings of the fascicles.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Sdcunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (1)