FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CortactinUAS.cSa
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General Information
Symbol
Dmel\CortactinUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Somogyi
FlyBase ID
FBal0156772
Feature type
allele
Associated gene
Dmel\Cortactin
Associated Insertion(s)
Carried in Construct
P{UAS-Cortactin.S}
Also Known As
UAS-cortactin
Key Links
Transgenic product class
wild_type
(Somogyi and Rorth, 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Somogyi and Rorth, 2004)
Mutagen
in vitro construct
(Somogyi and Rorth, 2004)
Progenitor genotype
Carried in construct
P{UAS-Cortactin.S}
Cytology
Description

UAS sequences drive expression of Cortactin.

(Somogyi and Rorth, 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Cortactin
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Alzheimer's disease 1
      modeled by Hsap\APPAβ42.UAS.Tag:SS(rPENK)
      (Cheng et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When CortactinScer\UAS.cSa is driven by Scer\GAL4Act5C.PP in somatic clones in the follicle cells, an increase is seen in the accumulation of F-actin. These cells also form shirt, Cortactin and F-actin rich protrusions and filopodia.

      (Somogyi and Rorth, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CortactinScer\UAS.cSa
      CortactinUAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Somogyi
      (Somogyi and Rorth, 2004)
      Secondary FlyBase IDs
        References (3)