FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\moodyEP1529
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General Information
Symbol
Dmel\moodyEP1529
Species
D. melanogaster
Name
FlyBase ID
FBal0156971
Feature type
allele
Associated gene
Dmel\moody
Associated Insertion(s)
P{EP}moodyEP1529
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EP}moodyEP1529
    Cytology
    Description

    The P{EP} insertion is within the 5' UTR of CG4322.

    (Kunwar et al., 2003)
    Allele components
    Component
    Use(s)
    Inserted element
    P{EP}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        moodyEP1529 flies are fully viable and show normal levels of climbing and locomotion. However, these flies show increased sensitivity to cocaine and nicotine, as measured by their behavorial responses. In contrast, these flies are resistant to the intoxicating effects of ethanol as they have an increased mean elution time from the inebriometer, although their ethanol absorbance is normal.

        The blood-brain barrier is not affected in moodyEP1529 flies.

        (Bainton et al., 2005)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CG4322EP1529
        moodyEP1529
        Name Synonyms
        Secondary FlyBase IDs
          References (2)