FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SgpEY06744
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General Information
Symbol
Dmel\SgpEY06744
Species
D. melanogaster
Name
FlyBase ID
FBal0157201
Feature type
allele
Associated gene
Dmel\Sgp
Associated Insertion(s)
P{EPgy2}SgpEY06744
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}SgpEY06744
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      SgpEY06744 homozygotes exhibit a significant increase in adult body weight with a larger abdominal adult fat mass while they exhibit normal pupariation time without any obvious defects during development and a normal adult lifespan when compared to controls.

      SgpEY06744 homozygous adults exhibit increased mortality upon systemic infection with Drosophila C virus (without an increase in viral titers), cricket paralysis virus (without an increase in viral titers) or Flock House virus but not with Drosophila X virus, and they exhibit a small but significant decreased mortality upon systemic infection with invertebrate iridescent virus 6 while they do not exhibit any changes in their life span upon heat induction or starvation when compared to controls.

      (Merkling et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG13091EY06744
      EY06744
      (Merkling et al., 2019)
      SgpEY06744
      Name Synonyms
      Secondary FlyBase IDs
        References (2)