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General Information
Symbol
Dmel\ptchh-ptc.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0158765
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

The N terminal signalling portion of hh (aa 1-256) are joined via three Tag:HA tags to the juxtamembrane and transmembrane portions of sev joined to the N terminus of full length ptc.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of ptchh-ptc.Scer\UAS.T:Ivir\HA1, under the control of Scer\GAL4ptc-559.1 results in the absence of ganglionic branch extension into the ventral nerve cord, along with defects in the dorsal branch, elongation and in dorsal trunk thickness and convolution are also observed. In addition, the visceral branches are very often misplaced, localising more ventrally than in the wild-type.

Overexpression of ptchh-ptc.Scer\UAS.T:Ivir\HA1 in all tracheal cells, under the control of Scer\GAL4btl.PS, does not induce a significant tracheal phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
ptchh-ptc.Scer\UAS.T:Ivir\HA1
ptchh-ptc.UAS.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (2)