FlyBase Allele Report: Dmel\numb[EY03840]

General Information

Symbol

Dmel\numb^EY03840

Species

D. melanogaster

Name

FlyBase ID

FBal0158873

Feature type

allele

Associated gene

Dmel\numb

Associated Insertion(s)

P{EPgy2}numb^EY03840

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}numb^EY03840

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:9,460,312..9,460,312 [+]

(Mujizah et al., 2024, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

axon | embryonic stage

(Mujizah et al., 2024)

larval intersegmental nerve | embryonic stage

(Mujizah et al., 2024)

ommatidium | somatic clone

(Domingos et al., 2019)

PNS neuron | embryonic stage

(Mujizah et al., 2024)

PNS neuron | embryonic stage (with Df(2L)N22-3)

(Mujizah et al., 2024)

PNS neuron | embryonic stage (with Df(2L)γ7)

(Mujizah et al., 2024)

PNS neuron | embryonic stage (with numb¹)

(Mujizah et al., 2024)

Detailed Description

Statement

Reference

numb^EY03840 clones generated in the larval eye disc lead to rare ommatidial rotation phenotypes - i.e. planar cell polarity defects.

(Domingos et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

19912

y¹ w^67c23; P{EPgy2}numb^EY03840/CyO

Kyoto

114573

y^d2 w¹¹¹⁸ P{ey-FLP.N}2; P{EPgy2}numb^EY03840 P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

numb^EY03840

(Mujizah et al., 2024)

numb^EY3840

(Domingos et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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