FlyBase Allele Report: Dmel\l(3)S033513[S033513]

General Information

Symbol

Dmel\l(3)S033513^S033513

Species

D. melanogaster

Name

FlyBase ID

FBal0159053

Feature type

allele

Associated gene

l(3)S033513

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Mathe et al., 2000)

Mutagen

Delta2-3 transposase

(Deak et al., 1997)

P-element activity

(Szeged Stock Center, 1998-)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile | recessive

(Mathe et al., 2000)

fertile | female (with Df(3R)by62)

(Mason et al., 2003)

fertile | female (with Df(3R)by416)

(Mason et al., 2003)

fertile | female (with Df(3R)GB104)

(Mason et al., 2003)

increased cell death | oogenesis

(Mathe et al., 2000)

lethal

(Mason et al., 2003)

lethal (with Df(3R)by62)

(Deak et al., 1997)

lethal | recessive

(Mathe et al., 2000, Deak et al., 1997)

sterile

(Mason et al., 2003)

viable (with Df(3R)by62)

(Mason et al., 2003)

viable (with Df(3R)by416)

(Mason et al., 2003)

viable (with Df(3R)GB104)

(Mason et al., 2003)

Phenotype Manifest In

egg chamber

(Mathe et al., 2000)

ovariole

(Mathe et al., 2000)

ovary

(Mathe et al., 2000)

Detailed Description

Statement

Reference

Brains of third instar mutant larvae exhibit a wild-type mitotic index. Homozygous mutants females have defective ovaries that have fewer ovarioles and degenerated egg chambers. Typically the egg chambers degenerate at stage 7-10 of oogenesis, although in some ovaries one or two eggs may reach maturity, but they are never released from the ovaries.

(Mathe et al., 2000)

Lethal phase is from the pharate adult stage onwards.

(Deak et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

l(3)S033513^S033513 has phenotype, suppressible by Kap-α3^+t9

(Mathe et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Separable from: Kap-α3^S033513.

(Mason et al., 2003)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

0335/13

(Deak et al., 1997)

l(3)S033513^S033513

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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