FlyBase Allele Report: Dmel\IKKβ[EY02434]

General Information

Symbol

Dmel\IKKβ^EY02434

Species

D. melanogaster

Name

FlyBase ID

FBal0159139

Feature type

allele

Associated gene

Dmel\IKKβ

Associated Insertion(s)

P{EPgy2}IKKβ^EY02434

Carried in Construct

Also Known As

ird5^EY02434

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}IKKβ^EY02434

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:16,049,390..16,049,390 [-]

(Liao et al., 2023, Radyuk et al., 2010, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Gene Disruption Project members, 2001-)

viable

(Gene Disruption Project members, 2001-)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

IKKβ^EY02434, Scer\GAL4^GMR.PFa is a suppressor | partially of visible | adult stage phenotype of Arms^GD10065, Scer\GAL4^GMR.PFa

(Liao et al., 2023)

Phenotype Manifest In

Enhancer of

Statement

Reference

ird5[+]/IKKβ^EY02434 is an enhancer of phenotype of Sindbis\rep^UAS.GFP

(Avadhanula et al., 2009)

Suppressor of

Statement

Reference

IKKβ^EY02434, Scer\GAL4^GMR.PFa is a suppressor | partially of eye phenotype of Arms^GD10065, Scer\GAL4^GMR.PFa

(Liao et al., 2023)

IKKβ^EY02434, Scer\GAL4^GMR.PFa is a suppressor | partially of autophagosome | increased number | adult stage phenotype of Arms^GD10065, Scer\GAL4^GMR.PFa

(Liao et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Heterozygosity for ird5^EY02434 in a Scer\GAL4^Act5C.PI Zzzz\rep^{Scer\UAS.T:Avic\GFP} background results in increased Sindbis viral replication.

(Avadhanula et al., 2009)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

19825

y¹ w^67c23; P{EPgy2}IKKβ^EY02434

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

IKKβ^EY02434

(Liao et al., 2023)

ird5^EY02434

(Radyuk et al., 2010, Davis et al., 2008)

ird5^ey02434

(Avadhanula et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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