FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fjUn.UAS
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General Information
Symbol
Dmel\fjUn.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0159231
Feature type
allele
Associated gene
Dmel\fj
Associated Insertion(s)
Carried in Construct
P{UAS-fj.Un}
Key Links
Transgenic product class
missense_variant
(Strutt et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Strutt et al., 2004)
Mutagen
in vitro construct
(Strutt et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-fj.Un}
Cytology
Description

UAS regulatory sequences drive expression of the full-length fj open reading frame, carrying amino acid substitutions (V87F and A91M) in two predicted sites for signal peptidase cleavage (a third potential signal peptidase cleavage site predicted in the ORF is not mutated). This results in impaired cleavage of the encoded protein; the cleaved C-terminus of fj was not detected in larval extracts expressing this transgene.

(Strutt et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
fj
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Anterior and posterior crossveins are closer together in the wings of fjUn.Scer\UAS; Scer\GAL4bi-omb-Gal4 flies than in wild-type. These flies have eyes with several rows of inverted ommatidia at their dorsal and ventral edges.

      (Strutt et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Scer\UAS sequences drive the expression of mutated full length fj cDNA.

      (Strutt et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      fjUn.Scer\UAS
      fjUn.UAS
      fjUn
      (Strutt et al., 2004)
      fjUncleavable
      (Strutt et al., 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)