FlyBase Allele Report: Dmel\capu[EY12344]

General Information

Symbol

Dmel\capu^EY12344

Species

D. melanogaster

Name

FlyBase ID

FBal0159423

Feature type

allele

Associated gene

Dmel\capu

Associated Insertion(s)

P{EPgy2}capu^EY12344

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}capu^EY12344

Cytology

Description

The P{EPgy2} insertion is in the first common exon of the capu open reading frame.

(Rosales-Nieves et al., 2006)

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:3,884,414..3,884,414 [+]

(Wood et al., 2024, Rosales-Nieves et al., 2006, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Gene Disruption Project members, 2001-)

viable

(Gene Disruption Project members, 2001-)

Phenotype Manifest In

filamentous actin | oogenesis

(Wood et al., 2024)

meiotic spindle

(Wood et al., 2024)

oocyte

(Wood et al., 2024)

spindle microtubule | oogenesis

(Wood et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

capu^EY12344/capu[+] is a suppressor of embryonic head phenotype of mira^{αTub67C.mGFP6}

(Chang et al., 2011)

Other

Statement

Reference

capu^EY12344, spir¹ has oocyte phenotype

(Wood et al., 2024)

capu^EY12344, spir¹ has meiotic spindle phenotype

(Wood et al., 2024)

capu^EY12344, spir¹ has filamentous actin | oogenesis phenotype

(Wood et al., 2024)

capu^EY12344, spir¹ has spindle microtubule | oogenesis phenotype

(Wood et al., 2024)

capu^EY12344, wash^Δ185 has oocyte | oogenesis stage S7 phenotype

(Liu et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

The bicaudal phenotype of embryos derived from mira^{αTub67C.T:Avic\GFP-m6}/+ females is suppressed if the females are also heterozygous for capu^EY12344.

(Chang et al., 2011)

Oocytes of wash^Δ185 capu^EY12344 transheterozygous females undergo premature cytoplasmic streaming. The normal gradient of microtubule organisation that is seen in wild-type oocytes at stage 7 is lost in the mutant oocytes. The mutant stage 7 oocytes have disruptions in the cortical actin.

(Liu et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

20345

y¹ w^67c23; P{EPgy2}capu^EY12344

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

capu^EY12344

(Wood et al., 2024, Pinheiro et al., 2017, Chang et al., 2011, Liu et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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