FB2026_02 , released June 18, 2026
Allele: Dmel\Ugpf03515
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General Information
Symbol
Dmel\Ugpf03515
Species
D. melanogaster
Name
FlyBase ID
FBal0159572
Feature type
allele
Associated gene
Dmel\Ugp
Associated Insertion(s)
PBac{WH}Ugpf03515
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Bloomington Drosophila Stock Center, 2004.11.6)
Progenitor genotype
Associated Insertion(s)
PBac{WH}Ugpf03515
Cytology
Description
Allele components
Component
Use(s)
Inserted element
PBac{WH}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  galactosemia
      modeled by GaltΔ1AP2
      (Jumbo-Lucioni et al., 2016)
      Comments on Models/Modifiers Based on Experimental Evidence ( 1 )
       

      UGPf03515/UGPd07256 in transheterozygous combination exacerbates GaltΔ1AP2 galactosemia model.

      (Jumbo-Lucioni et al., 2016)
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      UGPf03515/+ and UGPf03515/UGPd07256 larvae exhibit uncoordinated and slower movements in righting assays compared to controls, which are more more severe in the heteroallelic background.

      Larval neuromuscular junctions in UGPf03515/+ and UGPf03515/UGPd07256 present significantly more synaptic boutons than controls, which are more severe in the heteroallelic background; UGPf03515/+ larvae also show increase number of synaptic branches; UGPf03515/UGPd07256 do not show defects in excitatory junctional current amplitude.

      (Jumbo-Lucioni et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      NOT Enhanced by
      NOT suppressed by
      Enhancer of
      Statement
      Reference

      Ugpd07256/Ugpf03515 is an enhancer of uncoordinated | larval stage phenotype of GaltΔ1AP2

      (Jumbo-Lucioni et al., 2016)
      NOT Enhancer of
      Statement
      Reference

      Ugpd07256/Ugpf03515 is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of GaltΔ1AP2

      (Jumbo-Lucioni et al., 2016)
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      Ugpd07256/Ugpf03515 has NMJ bouton | larval stage phenotype, non-enhanceable by GaltΔ1AP2/GaltΔ1AP2

      (Jumbo-Lucioni et al., 2016)
      NOT suppressed by
      Statement
      Reference

      Ugpd07256/Ugpf03515 has NMJ bouton | larval stage phenotype, non-suppressible by GaltΔ1AP2/GaltΔ1AP2

      (Jumbo-Lucioni et al., 2016)
      NOT Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Larval neuromuscular junctions in UGPf03515/UGPd07256, GaltΔ1AP2/+ do not show defects in excitatory junctional current amplitudes.

      (Jumbo-Lucioni et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      UGPf03515
      Ugpf03515
      dUGP1
      (Jumbo-Lucioni et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)