FB2026_02 , released June 18, 2026
Allele: Dmel\Tis11EY09433
Open Close
General Information
Symbol
Dmel\Tis11EY09433
Species
D. melanogaster
Name
FlyBase ID
FBal0159668
Feature type
allele
Associated gene
Dmel\Tis11
Associated Insertion(s)
P{EPgy2}Tis11EY09433
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}Tis11EY09433
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  tauopathy
      modeled by Hsap\MAPTGMR.Ex.PJ
      (Ambegaokar and Jackson, 2011)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Tis11[+]/Tis11EY09433 is an enhancer of visible phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)

      Scer\GAL4GMR.PS/Tis11EY09433 is an enhancer of visible phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)
      NOT Suppressor of
      Statement
      Reference

      Tis11[+]/Tis11EY09433 is a non-suppressor of visible phenotype of Scer\GAL4GMR.PU, Zzzz\CAGQ108.UAS

      (Ambegaokar and Jackson, 2011)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Tis11[+]/Tis11EY09433 is an enhancer of eye phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)

      Scer\GAL4GMR.PS/Tis11EY09433 is an enhancer of eye phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)
      NOT Suppressor of
      Statement
      Reference

      Tis11[+]/Tis11EY09433 is a non-suppressor of eye phenotype of Scer\GAL4GMR.PU, Zzzz\CAGQ108.UAS

      (Ambegaokar and Jackson, 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of Tis11EY09433 mildly enhances the apoptosis seen in flies overexpressing hid.

      (Ambegaokar and Jackson, 2011)
      Xenogenetic Interactions
      Statement
      Reference

      One copy of Tis11EY09433 under the control of Scer\GAL4GMR.PS enhances the rough eye phenotype seen in flies expressing Hsap\MAPTGMR.Ex.PJ. The same phenotype is seen when Tis11EY09433 is expressed under the control of Scer\GAL4GMR.PU.

      One copy of Tis11EY09433 does not suppress the rough eye phenotype seen in flies expressing Zzzz\CAGQ108.Scer\UAS under the control of Scer\GAL4GMR.PU.

      (Ambegaokar and Jackson, 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Tis11EY09433
      (Ambegaokar and Jackson, 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)