teqf01792 homozygous adults have significantly reduced 24-hour associative olfactory water-reward memory, compared to controls, with no effect on 3-min or 3-hour memory.
teqf01792/teqf01792 males and females live significantly longer and are smaller (also weigh significantly less) than wild type flies; food intake and female fecundity are not significantly altered in mutants. Male and female teqf01792/teqf01792 mutants are more resistant to starvation-induced mortality compared to wild type flies; male (but not female) mutants are also significantly more resistant to paraquat-induced oxidative stress. teqf01792/teqf01792 flies show slower glucose clearance kinetics.
Tequilaf01792 flies show a short-term memory defect. These flies also display a sugar response defect after 21 hours of starvation.
Tequila animals display a decrease in 24-hour long-term memory after odor-avoidance spaced training compared to wild-type flies. The mutants show a normal 24-hour memory capacity after massed training. After a single conditioning, the learning and 2-hour memory of Tequila mutants is not different to wild type, showing that short-term memory is not affected.
No obvious structural defects can be observed in the mushroom bodies of Tequilaf01792 flies.