FlyBase Allele Report: Dmel\spz3[EY06670]

General Information

Symbol

Dmel\spz3^EY06670

Species

D. melanogaster

Name

FlyBase ID

FBal0159734

Feature type

allele

Associated gene

Dmel\spz3

Associated Insertion(s)

P{EPgy2}spz3^EY06670

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}spz3^EY06670

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:7,875,767..7,875,767 [+]

(Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | first instar larval stage | recessive

(Coutinho-Budd et al., 2017)

abnormal neuroanatomy | third instar larval stage (with Df(2L)BSC142)

(Coutinho-Budd et al., 2017)

fertile

(Gene Disruption Project members, 2001-)

lethal - all die before end of first instar larval stage

(Coutinho-Budd et al., 2017)

viable

(Gene Disruption Project members, 2001-)

Phenotype Manifest In

embryonic/larval cell body glial cell | first instar larval stage

(Coutinho-Budd et al., 2017)

embryonic/larval cell body glial cell | third instar larval stage (with Df(2L)BSC142)

(Coutinho-Budd et al., 2017)

larval ventral nerve cord | first instar larval stage

(Coutinho-Budd et al., 2017)

Detailed Description

Statement

Reference

spz3^EY06670 homozygous first instar larval VNC and spz3^EY06670/Df(2L)BSC142 third instar larvae exhibit defects in cortex glial morphology when compared to controls.

(Coutinho-Budd et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

spz3^EY06670 is partially rescued by spz3^UAS.EGFP/Scer\GAL4^{DBD.wrapper.932i}/Hsim\VP16^AD.nrv2

(Coutinho-Budd et al., 2017)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

16402

y¹ w^67c23; P{EPgy2}spz3^EY06670

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Spz3^EY06670

(Coutinho-Budd et al., 2017)

Spz3^P

(Coutinho-Budd et al., 2017)

spz3^EY06670

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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