FlyBase Allele Report: Dmel\Rab1[e01287]

General Information

Symbol

Dmel\Rab1^e01287

Species

D. melanogaster

Name

FlyBase ID

FBal0159948

Feature type

allele

Associated gene

Dmel\Rab1

Associated Insertion(s)

PBac{RB}Rab1^e01287

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

piggyBac activity

Nature of the Allele

Allele class

Mutagen

piggyBac activity

(Bloomington Drosophila Stock Center, 2004.11.6)

Progenitor genotype

Associated Insertion(s)

PBac{RB}Rab1^e01287

Cytology

Description

Allele components

Component

Use(s)

Inserted element

PBac{RB}

gene trap

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:21,268,976..21,268,976 [-]

(Kohrs et al., 2021, Bloomington Drosophila Stock Center, 2004.11.6)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

dendritic tree | prepupal stage P1 | somatic clone

(Wang et al., 2018)

dendritic tree | pupal stage | somatic clone

(Wang et al., 2018)

larval dorsal multidendritic neuron ddaC | prepupal stage P1 | somatic clone

(Wang et al., 2018)

larval dorsal multidendritic neuron ddaC | pupal stage | somatic clone

(Wang et al., 2018)

Detailed Description

Statement

Reference

Rab1^e01287 mutant ddaC neuron clones show significantly simplified dendrite arbors with fewer dendritic termini in wandering third instar larvae and show strong pruning defects in pupae (16h APF).

(Wang et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

The male sterility and meiotic cytokinesis phenotypes characteristic for Rab1^Z4144 mutants cannot be complemented by Rab1^e01287.

(Sechi et al., 2017)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

17936

w¹¹¹⁸; PBac{RB}Rab1^e01287/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Rab1^e01287

(Wang et al., 2018, Sechi et al., 2017)

rab1^e01287

(Sekine et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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