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General Information
Symbol
Dmel\M6EY07032
Species
D. melanogaster
Name
FlyBase ID
FBal0160210
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
M601
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{EPgy2}M6EY07032
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

M6EY07032 mutants do not exhibit defects in neuromuscular junctions or locomotion, but do exhibit defective long term memory.

The maximal lifespan in homozygous M6EY07032 mutant males is similar to controls. However, the median lifespan is significantly reduced compared to both heterozygous controls and wild type.

Homozygous M6EY07032 mutant males exhibit a mild rough eye phenotype, as well as a disorganised ommatidium array, defects in ommatidium shape and/or ommatidium fusion and defective or missing interommatidial bristles.

M6EY07032/M6MB02608 mutant males exhibit a mild rough eye phenotype, as well as a disorganised ommatidium array, defects in ommatidium shape and/or ommatidium fusion and defective or missing interommatidial bristles. Approximately 20% of M6EY07032/M6MB02608 transheterozygote eyes exhibit an excessive interommatidial space.

Young homozygous M6EY07032 mutant males exhibit a significantly defective phototactic response compared to controls. Locomotor activity in general appears to be unaffected.

Young transheterozygous M6EY07032/M6MB02608 mutant males exhibit a significantly defective phototactic response compared to controls. Locomotor activity in general appears to be unaffected.

Homozygous females lay a significantly reduced number of eggs compared to controls. Eggs laid by these females collapse soon after deposition, with almost 100% being collapsed within 20 minutes of laying. The mutant eggs are permeable to neutral red, in contrast to wild type.

Homozygous ovarioles do not show morphological defects at any stages of oogenesis.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)