FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gr28bc01884
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General Information
Symbol
Dmel\Gr28bc01884
Species
D. melanogaster
Name
FlyBase ID
FBal0160401
Feature type
allele
Associated gene
Dmel\Gr28b
Associated Insertion(s)
PBac{PB}Gr28bc01884
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Bloomington Drosophila Stock Center, 2004.11.6)
Progenitor genotype
Associated Insertion(s)
PBac{PB}Gr28bc01884
Cytology
Description
Allele components
Component
Use(s)
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Gr28bc01884 mutants exhibit a significant reduction in the light-induced response of class IV dendritic arborization neurons. However, the basal firing rate is not affected.

      (Xiang et al., 2010)

      Gr28bc01884 mutant flies eat at a significantly reduced rate compared to wild-type flies, and their ingestion volume is also reduced. Mutant flies also live longer than control flies.

      Gr28bc01884 mutant flies infected with L. monocytogenes die faster than wild-type flies, with an average median time to death of 4 days compared to 6-7 days for infected wild-type flies.

      Gr28bc01884 mutant flies infected with S. typhimurium live much longer than wild-type flies, with an average median time to death of 15 days compared to 8 days for infected wild-type flies.

      Gr28bc01884 mutant flies infected with E. faecalis die at the same rate as infected wild-type flies.

      Less than 10% of Gr28bc01884 mutants infected with either S. typhimurium or L. monocytogenes exhibit melanization, compared with over 90% of wild-type flies.

      (Ayres and Schneider, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Gr28bPBac01884
      (Guntur et al., 2015)
      Gr28bc01884
      (Ayres and Schneider, 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)