FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\MsrAEY05753
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General Information
Symbol
Dmel\MsrAEY05753
Species
D. melanogaster
Name
FlyBase ID
FBal0160502
Feature type
allele
Associated gene
Dmel\MsrA
Associated Insertion(s)
P{EPgy2}MsrAEY05753
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}MsrAEY05753
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eip71CDEY05753 mutant adults exhibit reduced susceptibility to infection with Vibrio cholerae: their post-infection survival rate is significantly increased compared to wild-type controls (despite comparable bacterial loads). Infected Eip71CDEY05753 mutant flies show normal lipid droplet accumulation in the fat body and enterocytes and the intestinal stem cell division is equally suppressed in control and the mutant flies (be the flies infected with either the wt or the Dgr;&gcvT strain of V. cholerae).

      (Vanhove et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      MsrAEY05753, Scer\GAL4B11-98 is a non-suppressor of macrochaeta phenotype of MicalUAS.s, Scer\GAL4B11-98

      (Hung et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Eip71CDEY05753
      MsrAEY05753
      (Vanhove et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)