FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CycHEP3658
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General Information
Symbol
Dmel\CycHEP3658
Species
D. melanogaster
Name
FlyBase ID
FBal0160668
Feature type
allele
Associated gene
Dmel\CycH
Associated Insertion(s)
P{EP}CycHEP3658
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EP}CycHEP3658
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{EP}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of CycHEP3658 under the control of Scer\GAL4ptc-559.1 (the animals are initially raised at 18oC and then shifted to 29oC after 10 days) causes 16-cell spermatogonial cysts to undergo cell death rather than to differentiate into spermatocytes. This defect is seen in at least 50% of testes examined.

        (Schulz et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        CycH[+]/CycHEP3658 is an enhancer of increased cell death phenotype of shtd1

        (Tanaka-Matakatsu et al., 2007)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        CycH[+]/CycHEP3658 is an enhancer of eye phenotype of shtd1

        (Tanaka-Matakatsu et al., 2007)

        CycH[+]/CycHEP3658 is an enhancer of ommatidium phenotype of shtd1

        (Tanaka-Matakatsu et al., 2007)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CycHEP3658
        EP3658
        (Tanaka-Matakatsu et al., 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)