FlyBase Allele Report: Dmel\casp[c04227]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\casp^c04227

General Information

Symbol

Dmel\casp^c04227

Species

D. melanogaster

Name

FlyBase ID

FBal0160923

Feature type

allele

Associated gene

Associated Insertion(s)

PBac{PB}casp^c04227

Carried in Construct

Also Known As

casp^lof

Key Links

Genomic Maps

Allele class

Mutagen

piggyBac activity

Nature of the Allele

Allele class

Mutagen

piggyBac activity

(Bloomington Drosophila Stock Center, 2004.11.6)

Progenitor genotype

Associated Insertion(s)

PBac{PB}casp^c04227

Cytology

Description

Allele components

Component

Use(s)

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:16,027,967..16,027,967 [+]

(Das et al., 2024, Bloomington Drosophila Stock Center, 2004.11.6)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

centrosome | embryonic stage | maternal effect (with Df(2R)BSC308)

(Das et al., 2024)

embryonic/larval cuticle | embryonic stage (with Df(2R)BSC308)

(Das et al., 2024)

filamentous actin | embryonic stage | maternal effect (with Df(2R)BSC308)

(Das et al., 2024)

nucleus | embryonic stage | maternal effect (with Df(2R)BSC308)

(Das et al., 2024)

pole bud | decreased number | embryonic stage (with Df(2R)BSC308)

(Das et al., 2024)

primordial germ cell | decreased number | embryonic stage | maternal effect (with Df(2R)BSC308)

(Das et al., 2024)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Df(2R)BSC308/casp^c04227 is rescued by Scer\GAL4^{VP16.nanos.UTR}/casp^ΔUBA.UASp

(Das et al., 2024)

Df(2R)BSC308/casp^c04227 is rescued by Scer\GAL4^{VP16.nanos.UTR}/casp^UAS.Tag:HA

(Das et al., 2024)

casp^c04227 is rescued by Scer\GAL4^{VP16.nanos.UTR}/casp^UAS.Tag:HA

(Das et al., 2024)

Partially rescued by

Df(2R)BSC308/casp^c04227 is partially rescued by casp^ΔFFAT.UASp/Scer\GAL4^{VP16.nanos.UTR}

(Das et al., 2024)

Df(2R)BSC308/casp^c04227 is partially rescued by Scer\GAL4^{VP16.nanos.UTR}/casp^ΔUAS.UASp

(Das et al., 2024)

Df(2R)BSC308/casp^c04227 is partially rescued by casp^ΔUBX.UASp/Scer\GAL4^{VP16.nanos.UTR}

(Das et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

11373

w¹¹¹⁸; PBac{PB}casp^c04227

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

CG8400^c04227

Casp^lof

(Das et al., 2024)

casp^c04227

casp^lof

(Kaduskar et al., 2020)

caspar^lof

(Tendulkar et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections