FB2026_02 , released June 18, 2026
Allele: Dmel\Pex16EY05323
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General Information
Symbol
Dmel\Pex16EY05323
Species
D. melanogaster
Name
FlyBase ID
FBal0161441
Feature type
allele
Associated gene
Dmel\Pex16
Associated Insertion(s)
P{EPgy2}Pex16EY05323
Carried in Construct
Also Known As
pex16EY
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}Pex16EY05323
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  peroxisome biogenesis disorder 8A
      CEA
      (Wangler et al., 2017)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Pex16EY05323/Df(3L)BSC563 transheterozygous adults show severely reduced activity under standard diet, do not show bang sensitivity, and do not show significant changes in electroretinogram amplitude, but show increased numbers of mitochondria and of electron-dense inclusions in photoreceptor cells, as compared to controls. These mutants survive for less time than controls under either complete starvation or low-sugar diet.

      (Wangler et al., 2017)

      pex16EY05323 mutants exhibit a cytokinesis defect.

      (Chen et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      Df(3L)BSC563/Pex16EY05323 has abnormal flight phenotype, non-suppressible by Dp(3;2)CH322-115M13

      (Wangler et al., 2017)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Pex16EY05323/Df(3L)BSC563 transheterozygous adults do not show bang sensitivity or significant changes in electroretinogram amplitude, regardless of also carrying Dp(3;2)CH322-115M13 or not.

      (Wangler et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CG3947EY05323
      Pex16EY05323
      (Wangler et al., 2025, Wangler et al., 2017)
      pex16EY05323
      pex16EY
      (Wangler et al., 2025, Wangler et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)