FB2026_02 , released June 18, 2026
Allele: Dmel\Sfxn1-3d06383
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General Information
Symbol
Dmel\Sfxn1-3d06383
Species
D. melanogaster
Name
FlyBase ID
FBal0162534
Feature type
allele
Associated gene
Dmel\Sfxn1-3
Associated Insertion(s)
P{XP}Sfxn1-3d06383
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Bloomington Drosophila Stock Center, 2004.11.6)
Progenitor genotype
Associated Insertion(s)
P{XP}Sfxn1-3d06383
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{XP}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  tauopathy
      modeled by Hsap\MAPTUAS.B
      (Minjarez et al., 2016)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      CG11739d06383 adult flies do not show any significant eye morphological abnormalities.

      (Minjarez et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      NOT Enhancer of
      Phenotype Manifest In
      Enhancer of
      NOT Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The defective eye morphology (disrupted ommatidial lattice) observed in adult flies expressing Hsap\MAPTScer\UAS.B under the control of Scer\GAL4GMR.PU is significantly enhanced by combination with CG11739d06383 as the eye size is much reduced.

      The glassy eye phenotype and disrupted ommatidial lattice observed in adult flies expressing Hsap\APP2xAPP.SP.Scer\UAS under the control of Scer\GAL4GMR.PU is not affected by combination with CG11739d06383.

      (Minjarez et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG11739d06383
      Sfxn1-3d06383
      Name Synonyms
      Secondary FlyBase IDs
        References (3)