FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\MntUAS.cLa
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General Information
Symbol
Dmel\MntUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Loo
FlyBase ID
FBal0176075
Feature type
allele
Associated gene
Dmel\Mnt
Associated Insertion(s)
Carried in Construct
P{UAS-Mnt.L}
Also Known As
UAS-Mnt
Key Links
Transgenic product class
wild_type
(Loo et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Loo et al., 2005)
Mutagen
in vitro construct
(Loo et al., 2005, Pierce et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Mnt.L}
Cytology
Description

UASt regulatory sequences drive expression of the Mnt isoform that contains both the SID and bHLHZ domains.

(Loo et al., 2005)

Expression of Mnt is under the control of UAS sequences.

(Pierce et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
UASt
Encoded product / tool
Mnt
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larval fat body cell clones expressing MntScer\UAS.cLa display fewer digesting autolysosomes than do wild-type cells.

      (Nagy et al., 2013)

      Expression of MntScer\UAS.cLa under the control of Scer\GAL4en-e16E results in a significantly smaller posterior compartment of the wing.

      Expression of MntScer\UAS.cLa under the control of Scer\GAL4ey.PH results in animals with small eye and head structures.

      (Loo et al., 2005)

      Clones in the wing disc expressing MntScer\UAS.cLa under the control of Scer\GAL4Act5C.PP are significantly smaller than control clones. There is an increase in the population of cells in the G[[0]]/G[[1]] phase of the cell cycle and a decrease in the population of cells in S and G[[2]]/M. The cells in the mutant clones are significantly smaller than those in the control clones.

      (Loo et al., 2005)

      Cells in MntScer\UAS.cLa; Scer\GAL4Act5C.PP somatic clones in the 2nd or 3rd instar larval fat body are smaller than their neighbours, and have significantly lower DNA content (assayed by DAPI fluorescence) than neighbouring cells.

      (Pierce et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Loo, Secombe and Eisenman

      (Pierce et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      MntScer\UAS.cLa
      MntUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Loo
      (Pierce et al., 2004)
      Secondary FlyBase IDs
        References (7)