FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tincUAS.cHa
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General Information
Symbol
Dmel\tincUAS.cHa
Species
D. melanogaster
Name
FlyBase ID
FBal0177456
Feature type
allele
Associated gene
Dmel\tinc
Associated Insertion(s)
Carried in Construct
P{UAS-tinc}
Key Links
Transgenic product class
wild_type
(Hirota et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hirota et al., 2005)
Mutagen
in vitro construct
(Hirota et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-tinc}
Cytology
Description

A 3.0kb EcoRI-XhoI DNA fragment containing the complete coding sequence (accession number AF509933) for tinc is driven under UASt regulatory sequences.

(Hirota et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tinc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of tincScer\UAS.cHa, under the control of Scer\GAL4GMR.PY results in disorganised eyes with fused ommatidia and collapsed photoreceptor cells.

      (Hirota et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      tincUAS.cHa/Scer\GAL4GMR.PY rescues tincRNAi.UAS

      (Hirota et al., 2005)
      Comments

      tincScer\UAS.cHa, under the control of Scer\GAL4GMR.PY completely rescues the disorganisation of the ommatidial array and the morphology of the photoreceptor cells found in flies in which tincdsRNA.Scer\UAS is expressed under the control of Scer\GAL4GMR.PY.

      (Hirota et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tincScer\UAS.cHa
      tincUAS.cHa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)