FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\shakBL.UAS
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General Information
Symbol
Dmel\shakBL.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0178019
Feature type
allele
Associated gene
Dmel\shakB
Associated Insertion(s)
Carried in Construct
P{UAS-shakB.L}
Key Links
Transgenic product class
cDNA
(Curtin et al., 2002)
wild_type
(Curtin et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Curtin et al., 2002)
wild_type
(Curtin et al., 2002)
Mutagen
in vitro construct
(Curtin et al., 2002, Curtin et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-shakB.L}
Cytology
Description

UAS regulatory sequences govern expression of the shakB L isoform cDNA. This is identical to the N isoform except for an approximately 20 amino acid difference in the first approximately 150 amino acids (FBrf080175).

(Curtin et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
shakB
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Statement
      Reference

      Scer\GAL4ogre.PC, shakBL.UAS has abnormal neurophysiology phenotype, non-suppressible by ogre2

      (Curtin et al., 2002)
      NOT Suppressor of
      Statement
      Reference

      shakBL.UAS, Scer\GAL4ogre.PC, Scer\GAL4hs.2sev is a non-suppressor of abnormal neurophysiology phenotype of ogre2

      (Curtin et al., 2002)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      shakBL.Scer\UAS expression in the retinal neurons of ogre2 mutants, under the simultaneous regulation of both Scer\GAL4ogre.PC and Scer\GAL4unspecified does not rescue the electroretinogram phenotype of ogre2 mutants.

      (Curtin et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      shakBL.Scer\UAS
      shakBL.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)