FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sc1-260.UAS
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General Information
Symbol
Dmel\sc1-260.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0178113
Feature type
allele
Associated gene
Dmel\sc
Associated Insertion(s)
Carried in Construct
P{UAS-sc.1-260}
Key Links
Transgenic product class
inframe_deletion
(Giagtzoglou et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Giagtzoglou et al., 2005)
Mutagen
in vitro construct
(Giagtzoglou et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-sc.1-260}
Cytology
Description

UAS regulatory sequences drive expression of a C-terminally truncated form of sc which terminates at amino acid 260.

(Giagtzoglou et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
sc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of sc1-260.Scer\UAS under the control of Scer\GAL4sca-C253 is able to induce sensory organ precursor cells in the wing disc, which result in bristles in the adult notum, in a Df(1)sc10-1 background.

      Co-expression of sc1-260.Scer\UAS and daΔAD1.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4sca-C253 is able to induce sensory organ precursor cells in the wing disc in a Df(1)sc10-1 background.

      Co-expression of sc1-260.Scer\UAS and daΔLH.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4sca-C253 is able to induce sensory organ precursor cells in the wing disc in a Df(1)sc10-1 background.

      Co-expression of sc1-260.Scer\UAS and daΔTADs.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4sca-C253 is unable to induce sensory organ precursor cells in the wing disc in a Df(1)sc10-1 background, save the occasional SOP escaper.

      (Zarifi et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sc1-260.Scer\UAS
      sc1-260.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)