FlyBase Allele Report: Dmel\mr[RNAi.UAS.cvRa]

General Information

Symbol

Dmel\mr^{RNAi.UAS.cvRa}

Species

D. melanogaster

Name

FlyBase ID

FBal0178830

Feature type

allele

Associated gene

Dmel\mr

Associated Insertion(s)

Carried in Construct

P{UAS-mr.RNAi.R}

Key Links

Transgenic product class

RNAi_reagent

(van Roessel et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(van Roessel et al., 2004)

Mutagen

in vitro construct

(van Roessel et al., 2004)

Progenitor genotype

Carried in construct

P{UAS-mr.RNAi.R}

Cytology

Description

UASt regulatory sequences drive expression of a repeat of a 632bp fragment of a mr exon (in antisense and then in sense orientation).

(van Roessel et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^elav-C155

(van Roessel et al., 2004)

Phenotype Manifest In

embryonic/larval neuromuscular junction, with Scer\GAL4^elav-C155

(van Roessel et al., 2004)

NMJ bouton | increased number, with Scer\GAL4^elav-C155

(van Roessel et al., 2004)

Detailed Description

Statement

Reference

Expression of mr^{dsRNA.Scer\UAS} under the control of Scer\GAL4^elav-C155 results in an approximately 20% increase in the number of boutons/muscle area at the neuromuscular junction in third instar larvae compared to controls. Expression of mr^{dsRNA.Scer\UAS} under the control of Scer\GAL4^how-24B has no effect on bouton number at the neuromuscular junction in third instar larvae.

(van Roessel et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

mr^{RNAi.UAS.cvRa}

mr^{dsRNA.Scer\UAS}

mr^dsRNA.UAS

mr^dsRNA

(Neuert et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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