APC2, dAPC2, APC2/mr
APC2 subunit of the anaphase promoting complex - Cullin homology protein - regulates protein degradation and cell cycle - regulates variant cell cycles, because in addition to disrupting the archetypal cycle (G1-S-G2-M), mutations affect the rapid embryonic divisions as well as the endo cycle that produces polyploid cells
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mr using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mr in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
mr is required to maintain the absence of mitosis during the endo cycle, and is also necessary for dividing cells to exit mitosis.
Bridges, 8th March 1913.