FB2026_02 , released June 18, 2026
Allele: Dmel\mtde00435
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General Information
Symbol
Dmel\mtde00435
Species
D. melanogaster
Name
FlyBase ID
FBal0179107
Feature type
allele
Associated gene
Dmel\mtd
Associated Insertion(s)
PBac{RB}mtde00435
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Wang et al., 2013)
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{RB}mtde00435
Cytology
Description

Transcription of mtd-RC and all long transcripts (containing the TLDc and LysM domains) is reduced, whereas mtd-RH is unaffected.

(Wang et al., 2012)
Allele components
Component
Use(s)
Inserted element
PBac{RB}
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Compared with wild-type, mtde00435/mtdKG02600 mutants show increased sensitivity to H[[2]]O[[2]] ingestion.

      (Wang et al., 2013)

      In contrast to mtdEY04695 flies, mtdf06038 mutants show increased susceptibility to V. cholerae infection.

      (Wang et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      E00435
      (Wang et al., 2012)
      l(3)82Fde00435
      mtdE00435
      (Wang et al., 2013)
      mtde00435
      Name Synonyms
      Secondary FlyBase IDs
        References (3)