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General Information
Symbol
Dmel\gcmN7-4DN.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0179659
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-glideN7-4DN, UAS-gcmN7-4DN
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS sequences drive expression of a fusion protein that consists of the gcm DNA-binding domain (amino acids 1-390) carrying the point mutation found in gcmN7-4 and fused to the en repressor domain (amino acid residues 1-304). The gcmN7-4 lesion renders the protein inactive.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Animals carrying gcmN7-4.DN.Scer\UAS.T:en-Rep, Scer\GAL4gcm-rA87.P and Scer\GAL80ts.╬▒Tub84B which are raised at 18[o]C until the early second larval instar stage and then transferred to 30[o]C show no defects in the migrating medulla neuropile glia.

Expression of gcmN7-4.DN.Scer\UAS.T:en-Rep, under the control of Scer\GAL4bi-omb-Gal4 does not affect R axon projection. Expression of gcmN7-4.DN.Scer\UAS.T:en-Rep, under the control of Scer\GAL4NP6099 does not affect R axon projection.

Stage 17 gcmN7-4.DN.Scer\UAS.T:en-Rep, Scer\GAL4ptc-559.1 embryos do not have the muscle attachment defects seen in gcmDN.Scer\UAS.T:en-Rep Scer\GAL4ptc-559.1 embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
gcmN7-4.DN.Scer\UAS.T:Rep-en
gcmN7-4.DN.Scer\UAS.T:en-Rep
gcmN7-4DN.Scer\UAS
gcmN7-4DN.UAS
Name Synonyms
Secondary FlyBase IDs
    References (5)