FB2026_02 , released June 18, 2026
Allele: Dmel\exuA6B3
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General Information
Symbol
Dmel\exuA6B3
Species
D. melanogaster
Name
FlyBase ID
FBal0179950
Feature type
allele
Associated gene
Dmel\exu
Associated Insertion(s)
Carried in Construct
P{exu.A6B3}
Key Links
Transgenic product class
missense_variant
(Riechmann and Ephrussi, 2004)
polypeptide_post_translational_processing_variant
(Riechmann and Ephrussi, 2004)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Riechmann and Ephrussi, 2004)
polypeptide_post_translational_processing_variant
(Riechmann and Ephrussi, 2004)
Mutagen
in vitro construct
(Riechmann and Ephrussi, 2004)
Progenitor genotype
Carried in construct
P{exu.A6B3}
Cytology
Description

The exu promoter drives expression of a mutated form of exu in which all par-1 phosphorylation sites within 14-3-3 protein binding sites A and B have been mutated; carries amino acid replacements S436A, S437A, S438A, S440A, S456A and S457A.

(Riechmann and Ephrussi, 2004)
Allele components
Component
Use(s)
Regulatory region(s)
exu
Encoded product / tool
exu
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      More than one-third of embryos derived from exuVL/exuXL1 ; exuA6B3 females develop head defects typical of exu mutants.

      (Riechmann and Ephrussi, 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      exuA6B3
      exuΔA+B
      (Riechmann and Ephrussi, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)