Mutated Slbp (carries the amino acid replacement T120A) tagged with two copies of Tag:HA at the N-terminus. The Slbp fragment corresponds to genomic sequence from the SacII site 612bp upstream of the start codon to the BamHI site 605 bp downstream of the stop codon. Expression is from the endogenous Slbp promoter.
SlbpT120A.Tag:HA partially rescues Slbp15/Df(3R)3450
Two copies of the SlbpT120A.T:Ivir\HA1 transgene fully recues the viability and fecundity of Slbp15/Df(3R)3450 flies. The viability of Slbp15/Df(3R)3450 mutants with one copy of SlbpT120A.T:Ivir\HA1 is usually rescued, depending on insertion of the transgene. Females rescued with one copy of SlbpT120A.T:Ivir\HA1 can be sterile or fertile, depending on the insertion, while males are always fertile.