FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hsp26UAS.Tag:HA
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General Information
Symbol
Dmel\Hsp26UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0183171
Feature type
allele
Associated gene
Dmel\Hsp26
Associated Insertion(s)
Carried in Construct
P{UAS-Hsp26.HA}
Key Links
Transgenic product class
cDNA
(Wang et al., 2004)
wild_type
(Wang et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wang et al., 2004)
wild_type
(Wang et al., 2004)
Mutagen
in vitro construct
(Wang et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Hsp26.HA}
Cytology
Description

UAS regulatory sequences drive expression of full length Hsp26 (from EST GM08850) tagged at the C-terminal end with Tag:HA.

(Wang et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsp26
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Hsp26Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4hs.PB at either 25 or 29oC in male flies results in an increase in mean lifespan compared to controls. Expression of Hsp26Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.G32 at 29oC in male flies results in an increase in mean lifespan compared to controls. Expression of Hsp26Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4hs.PB in male flies results in an increased resistance to paraquat and heat stress compared to controls, and a marginal increase in starvation resistance compared to controls. Females expressing Hsp26Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4hs.PB show a reduction in fecundity compared to controls, although there is no significant difference in hatching between eggs derived from these females and those derived from controls.

      (Wang et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsp26Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ey-OK107 partially suppresses the axon degeneration seen in bskflp147E mutant mushroom body neuron clones at 28 days.

      Expression of Hsp26Scer\UAS.T:Ivir\HA1 partially suppresses the mushroom body degeneration seen in 7 day old flies when NmnatJF03337 is expressed under the control of Scer\GAL4ey-OK107.

      (Rallis et al., 2013)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsp26Scer\UAS.T:Ivir\HA1
      Hsp26UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)